Learning Objectives:

1. Summarize the prevalence rate of persistent pain and its perceptual qualities associated with chronic ankle instability 2. Identify key central processing pathways involved in sensorimotor control and pain processing. 3. Interpret how alterations in sensorimotor and thalamocortical white matter pathways may contribute to persistent pain, altered movement patterns, and central nervous system involvement in chronic ankle instability.

Keywords: Magnetic Resonance Imaging; Brain; Injury